Öz
Objective: The aim of the study was to evaluate orthopedic patients' knowledge of antibiotics and antibiotic resistance.
Material and Method: Patients admitted to the hospital for orthopedic surgery were given a questionnaire containing a total of 26 questions, 7 multiple choices, nine true and false questions and ten likert scale questions adapted from a survey which has been published by World Health Organization and translated to Albanian to assess their knowledge and attitude toward antibiotics and antibiotic resistance.
Result and Discussion: Sixty-two percent of the patients misunderstood the definition of antibiotic resistance and answered yes to the question "Antibiotic resistance occurs when your body becomes resistant to antibiotics and the antibiotic is no longer effective." 62.4% of the patient strongly agreed that ‘antibiotic resistance is one of the biggest problems facing the world”. Although participants are aware of antibiotic resistance and the potential threats it may pose, their knowledge of the causes of antibiotic resistance and how to prevent it is limited. In conclusion, attempts need to be made to raise antibiotic resistance awareness and knowledge among the Kosovo population.
Anahtar Kelimeler
Destekleyen Kurum
Ortomedica Hospital
Kaynakça
- 1. Goto, T., Yoshida, K., Tsugawa, Y., Camargo Jr, C.A., Hasegawa, K. (2016). Infectious disease-related emergency department visits of elderly adults in the United States, 2011-2012. Journal of the American Geriatrics Society, 64(1), 31-36. [CrossRef]
- 2. Llor, C., Bjerrum, L. (2014). Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem. Therapeutic Advances in Drug Safety, 5(6), 229-241. [CrossRef]
- 3. Alharbi, M.H., Khormi, A.Y., Albisher, A.M., Barkoot, M.M., Alsofyani, B.A., Althabet, F.M., Aljehani, H.S. (2017). The dangerous effects of excessive use of antibiotics among community in Saudi Arabia. Egyptian Journal of Hospital Medicine, 69(5), 2493-2496. [CrossRef]
- 4. Laxminarayan, R., Duse, A., Wattal, C., Zaidi, A.K., Wertheim, H.F., Sumpradit, N., Vlieghe, E., Hara, G.L., Gould, I.M., Goossens, H., Greko, C., So, A.D., Bigdeli, M., Tomson, G., Woodhouse, W., Ombaka, E., Peralta, A.Q., Qamar, F.N., Mir, F., Kariuki, S., Cars, O. (2013). Antibiotic resistance-the need for global solutions. The Lancet Infectious Diseases, 13(12), 1057-1098. [CrossRef]
- 5. Akova, M. (2016). Epidemiology of antimicrobial resistance in bloodstream infections. Virulence, 7(3), 252-266. [CrossRef]
- 6. Ibraimi, Z., Shehi, A., Murtezani, A., Krasniqi, S., Agani, Z. (2015). Kosovo's public health damage from abusive use of antibiotics in dairy cattle. Mater Socio-Medica, 27(3), 149-153. [CrossRef]
- 7. Hawkey, P.M. (2015). Multidrug-resistant gram-negative bacteria: a product of globalization. The Journal of Hospital Infection, 89(4), 241-247. [CrossRef]
- 8. Pulingam, T., Parumasivam, T., Gazzali, A.M., Sulaiman, A.M., Chee, J.Y., Lakshmanan, M., Chin, C.F., Sudesh, K. (2022). Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome. European Journal of Pharmaceutical Sciences, 170, 106103. [CrossRef]
- 9. Baquero, F. (2021). Threats of antibiotic resistance: an obliged reappraisal. International Microbiology, 24(4), 499-506. [CrossRef]
- 10. Ahmad, A., Sundararajan, P., Patel, I., Praveen, N., Balkrishnan, R., Mohanta, G. (2012). Evaluation of self-medication antibiotics use pattern among patients attending community pharmacies in rural India, Uttar Pradesh. Journal of Pharmacy Research, 5, 765-768. [CrossRef]
- 11. Oxman, D.A., Issa, N.C., Marty, F.M., Patel, A., Panizales, C.Z., Johnson, N.N., Licona, J.H., McKenna, S.S., Frendl, G., Mentzer, S.J., Jaklitsch, M.T., Bueno, R., Colson, Y., Swanson, S.J., Sugarbaker, D.J., Baden, L.R. (2013). Postoperative antibacterial prophylaxis for the prevention of infectious complications associated with tube thoracostomy in patients undergoing elective general thoracic surgery: a double-blind, placebo-controlled, randomized trial. JAMA Surgery, 148(5), 440-446. [CrossRef]
- 12. Musmar, S.M., Ba’ba, H., Owais, A. (2014). Adherence to guidelines of antibiotic prophylactic use in surgery: a prospective cohort study in North West Bank, Palestine. BMC Surgery, 14(69), 1-7. [CrossRef]
- 13. World Health Organization Web site. (2016). Retrieved November 5, 2022 from https://www.euro.who.int/. Accessed date: 05.11.2022.
- 14. Uchil, R.R., Kohli, G.S., Katekhaye, V.M., Swami, O.C. (2014). Strategies to combat antimicrobial resistance. Journal of Clinical and Diagnostic Research: JCDR, 8(7), ME01-ME4. [CrossRef]
- 15. de With, K., Allerberger, F., Amann, S., Apfalter, P., Brodt, H.R., Eckmanns, T., Fellhauer, M., Geiss, H.K., Janata, O., Krause, R., Lemmen, S., Meyer, E., Mittermayer, H., Porsche, U., Presterl, E., Reuter, S., Sinha, B., Strauß, R., Wechsler-Fördös, A., Wenisch, C., Kern, W.V. (2016). Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases. Infection, 44(3), 395-439. [CrossRef]
- 16. World Health Organization antibiotic resistance: multi-country public awaresness survey. (2015). Retrieved August 2, 2018, from https://apps.who.int/iris/bitstream/handle/10665/194460/9789241509817_eng.pdf. Accessed date: 02.08.2018
- 17. Sakeena, M.H.F., Bennett, A.A., Carter, S.J., McLachlan, A.J. (2019). A comparative study regarding antibiotic consumption and knowledge of antimicrobial resistance among pharmacy students in Australia and Sri Lanka. Plos One, 14(3), 1-14. [CrossRef]
- 18. Elden, N.M.K., Nasser, H.A., Alli, A., Mahmoud, N., Shawky, M.A., Ibrahim, A.A.E.A., Fahmy, A.K. (2020). Risk factors of antibiotics self-medication practices among university students in Cairo, Egypt. Open Access Macedonian Journal of Medical Sciences, 8(E), 7-12. [CrossRef]
- 19. Elmasry, A.A.G., Bakr, A.S.M., Kolkailah, D.A.A.A., Khaskia, M.A.I., Mohammed, M.E.E., Riad, O.H.M.A., Abdelrahman, S.A.K. (2013). Pattern of antibiotic abuse - a population based study in Cairo. Egyptian Journal of Chest Diseases and Tuberculosis, 62(1), 189-195. [CrossRef]
- 20. Badger-Emeka, L.I., Emeka, P.M., Okosi, M. (2018). Evaluation of the extent and reasons for increased non-prescription antibiotics use in a university town, Nsukka Nigeria. International Journal of Health Sciences, 12(4), 11-17.
- 21. West, L.M., Cordina, M. (2019). Educational intervention to enhance adherence to short-term use of antibiotics. Research in Social and Administrative Pharmacy, 15(2), 193-201. [CrossRef]
Öz
Amaç: Bu çalışmanın amacı ortopedi hastalarının antibiyotikler ve antibiyotik direnci üzerine bilgisini değerlendirmektir.
Gereç ve Yöntem: Ortopedi ameliyatı için hastaneye yatırılan hastaların antibiyotikler ve antibiyotik direnci üzerine bilgilerini ve tutumlarını değerlendirmek amacı ile Dünya Sağlık Örgütü tarafından uygulanmış bir anketten uyarlama Arnavutça’ya çevrilen 7 adet çoktan seçmeli, 9 adet doğru yanlış ve 10 adet likert ölçeği sorusu olmak üzere toplamda 26 sorudan oluşan uyarlama anket yöneltildi.
Sonuç ve Tartışma: Hastaların yüzde 62’si antibiyotik direncinin tanımını yanlış anlamış ve "Antibiyotik direnci, vücudunuz antibiyotiklere dirençli hale geldiğinde ve artık işe yaramadığında ortaya çıkar." sorusuna evet cevabını vermiştir. Hastaların yüzde 62.4’ü "Antibiyotik direnci dünyanın karşı karşıya olduğu en büyük sorunlardan biridir." ifadesine kesinlikle katıldıklarını belirtmiştir. Katılımcılar antibiyotik direncinin ve sebep olması muhtemel tehlikelerin farkında olmalarına ragmen, antibiyotik direncinin sebeplerine ve antibiyotik direncinin nasıl önleneceğine dair bilgileri kısıtlıdır. Sonuç olarak, Kosova’da antibiyotik direncine dair bilinç ve farkındalığı arttırmaya yönelik çalışmalar yapılması gerekmektedir.
Anahtar Kelimeler
Kaynakça
- 1. Goto, T., Yoshida, K., Tsugawa, Y., Camargo Jr, C.A., Hasegawa, K. (2016). Infectious disease-related emergency department visits of elderly adults in the United States, 2011-2012. Journal of the American Geriatrics Society, 64(1), 31-36. [CrossRef]
- 2. Llor, C., Bjerrum, L. (2014). Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem. Therapeutic Advances in Drug Safety, 5(6), 229-241. [CrossRef]
- 3. Alharbi, M.H., Khormi, A.Y., Albisher, A.M., Barkoot, M.M., Alsofyani, B.A., Althabet, F.M., Aljehani, H.S. (2017). The dangerous effects of excessive use of antibiotics among community in Saudi Arabia. Egyptian Journal of Hospital Medicine, 69(5), 2493-2496. [CrossRef]
- 4. Laxminarayan, R., Duse, A., Wattal, C., Zaidi, A.K., Wertheim, H.F., Sumpradit, N., Vlieghe, E., Hara, G.L., Gould, I.M., Goossens, H., Greko, C., So, A.D., Bigdeli, M., Tomson, G., Woodhouse, W., Ombaka, E., Peralta, A.Q., Qamar, F.N., Mir, F., Kariuki, S., Cars, O. (2013). Antibiotic resistance-the need for global solutions. The Lancet Infectious Diseases, 13(12), 1057-1098. [CrossRef]
- 5. Akova, M. (2016). Epidemiology of antimicrobial resistance in bloodstream infections. Virulence, 7(3), 252-266. [CrossRef]
- 6. Ibraimi, Z., Shehi, A., Murtezani, A., Krasniqi, S., Agani, Z. (2015). Kosovo's public health damage from abusive use of antibiotics in dairy cattle. Mater Socio-Medica, 27(3), 149-153. [CrossRef]
- 7. Hawkey, P.M. (2015). Multidrug-resistant gram-negative bacteria: a product of globalization. The Journal of Hospital Infection, 89(4), 241-247. [CrossRef]
- 8. Pulingam, T., Parumasivam, T., Gazzali, A.M., Sulaiman, A.M., Chee, J.Y., Lakshmanan, M., Chin, C.F., Sudesh, K. (2022). Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome. European Journal of Pharmaceutical Sciences, 170, 106103. [CrossRef]
- 9. Baquero, F. (2021). Threats of antibiotic resistance: an obliged reappraisal. International Microbiology, 24(4), 499-506. [CrossRef]
- 10. Ahmad, A., Sundararajan, P., Patel, I., Praveen, N., Balkrishnan, R., Mohanta, G. (2012). Evaluation of self-medication antibiotics use pattern among patients attending community pharmacies in rural India, Uttar Pradesh. Journal of Pharmacy Research, 5, 765-768. [CrossRef]
- 11. Oxman, D.A., Issa, N.C., Marty, F.M., Patel, A., Panizales, C.Z., Johnson, N.N., Licona, J.H., McKenna, S.S., Frendl, G., Mentzer, S.J., Jaklitsch, M.T., Bueno, R., Colson, Y., Swanson, S.J., Sugarbaker, D.J., Baden, L.R. (2013). Postoperative antibacterial prophylaxis for the prevention of infectious complications associated with tube thoracostomy in patients undergoing elective general thoracic surgery: a double-blind, placebo-controlled, randomized trial. JAMA Surgery, 148(5), 440-446. [CrossRef]
- 12. Musmar, S.M., Ba’ba, H., Owais, A. (2014). Adherence to guidelines of antibiotic prophylactic use in surgery: a prospective cohort study in North West Bank, Palestine. BMC Surgery, 14(69), 1-7. [CrossRef]
- 13. World Health Organization Web site. (2016). Retrieved November 5, 2022 from https://www.euro.who.int/. Accessed date: 05.11.2022.
- 14. Uchil, R.R., Kohli, G.S., Katekhaye, V.M., Swami, O.C. (2014). Strategies to combat antimicrobial resistance. Journal of Clinical and Diagnostic Research: JCDR, 8(7), ME01-ME4. [CrossRef]
- 15. de With, K., Allerberger, F., Amann, S., Apfalter, P., Brodt, H.R., Eckmanns, T., Fellhauer, M., Geiss, H.K., Janata, O., Krause, R., Lemmen, S., Meyer, E., Mittermayer, H., Porsche, U., Presterl, E., Reuter, S., Sinha, B., Strauß, R., Wechsler-Fördös, A., Wenisch, C., Kern, W.V. (2016). Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases. Infection, 44(3), 395-439. [CrossRef]
- 16. World Health Organization antibiotic resistance: multi-country public awaresness survey. (2015). Retrieved August 2, 2018, from https://apps.who.int/iris/bitstream/handle/10665/194460/9789241509817_eng.pdf. Accessed date: 02.08.2018
- 17. Sakeena, M.H.F., Bennett, A.A., Carter, S.J., McLachlan, A.J. (2019). A comparative study regarding antibiotic consumption and knowledge of antimicrobial resistance among pharmacy students in Australia and Sri Lanka. Plos One, 14(3), 1-14. [CrossRef]
- 18. Elden, N.M.K., Nasser, H.A., Alli, A., Mahmoud, N., Shawky, M.A., Ibrahim, A.A.E.A., Fahmy, A.K. (2020). Risk factors of antibiotics self-medication practices among university students in Cairo, Egypt. Open Access Macedonian Journal of Medical Sciences, 8(E), 7-12. [CrossRef]
- 19. Elmasry, A.A.G., Bakr, A.S.M., Kolkailah, D.A.A.A., Khaskia, M.A.I., Mohammed, M.E.E., Riad, O.H.M.A., Abdelrahman, S.A.K. (2013). Pattern of antibiotic abuse - a population based study in Cairo. Egyptian Journal of Chest Diseases and Tuberculosis, 62(1), 189-195. [CrossRef]
- 20. Badger-Emeka, L.I., Emeka, P.M., Okosi, M. (2018). Evaluation of the extent and reasons for increased non-prescription antibiotics use in a university town, Nsukka Nigeria. International Journal of Health Sciences, 12(4), 11-17.
- 21. West, L.M., Cordina, M. (2019). Educational intervention to enhance adherence to short-term use of antibiotics. Research in Social and Administrative Pharmacy, 15(2), 193-201. [CrossRef]
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Eczacılık ve İlaç Bilimleri |
| Bölüm | Araştırma Makalesi |
| Yazarlar | |
| Erken Görünüm Tarihi | 17 Mayıs 2023 |
| Yayımlanma Tarihi | 20 Mayıs 2023 |
| Gönderilme Tarihi | 20 Aralık 2022 |
| Kabul Tarihi | 17 Şubat 2023 |
| Yayımlandığı Sayı | Yıl 2023 Cilt: 47 Sayı: 2 |
Kaynak Göster
Kapsam ve Amaç
Ankara Üniversitesi Eczacılık Fakültesi Dergisi, açık erişim, hakemli bir dergi olup Türkçe veya İngilizce olarak farmasötik bilimler alanındaki önemli gelişmeleri içeren orijinal araştırmalar, derlemeler ve kısa bildiriler için uluslararası bir yayım ortamıdır. Bilimsel toplantılarda sunulan bildiriler supleman özel sayısı olarak dergide yayımlanabilir. Ayrıca, tüm farmasötik alandaki gelecek ve önceki ulusal ve uluslararası bilimsel toplantılar ile sosyal aktiviteleri içerir.